Hiroaki Ito, Ph.D. (Doctor of Science)
伊藤 弘明　博士（理学）
Assistant Professor at Chiba University
Nonlinear Physics and Soft Matter Physics Lab.
Department of Physics
Graduate School of Science
Chiba University

Research

Keywords

Non-equilibrium interfacial phenomena as physics of biological soft interfaces,
Structure and function of soft interfaces in meso-scale,
Soft matter physics, Biophysics, Microfluidics, Physics of diseases, Medical application,Robotics

Physics of non-equilibrium interfacial phenomena,
crossing the hierarchical complexity

Biological interfaces not only divide the inner and outer worlds for living matters, but also play complex roles by consuming energy under a fluctuating environment. What functions and how much complexity are necessary to be "living"? What principles of what materials govern those living phenomena? I am trying to better understand the living interfacial phenomena from the viewpoint of physics, which can tackle the essential principles of materials.

Precise control for extracting characteristics of living matters

Living matters have individuality in their behaviors and responses. I am trying to extract the essential aspects of living systems, including the individuality, through the experiments based on precise controls and measurements, utilizing cutting-edge microfluidics and robotics.

Publications

Peer-reviewed papers

  1. "Pattern dynamics of the nonreciprocal Swift-Hohenberg model"
    Yuta Tateyama, Hiroaki Ito, Shigeyuki Komura, and Hiroyuki Kitahata
    Phys. Rev. E, 110, 054209 (2024). / arXiv:2407.05742
  2. "Deformation dynamics of an oil droplet into a crescent shape during intermittent motion"
    Sayaka Otani, Hiroaki Ito, Tomonori Nomoto, Masanori Fujinami, Jerzy Górecki, and Hiroyuki Kitahata
    Phys. Rev. E, 110, 044602 (2024). / arXiv:2402.01161
  3. "Aspect-ratio-dependent void formation in active rhomboidal and elliptical particle systems"
    Motoya Suzaka, Hiroaki Ito, and Hiroyuki Kitahata
    Phys. Rev. E, 110, 024609 (2024). / arXiv:2302.00308
  4. "Two-dimensional hydrodynamic simulation for synchronized oscillatory flows in two collapsible channels connected in parallel"
    Yuki Araya, Hiroaki Ito, and Hiroyuki Kitahata
    Phys. Rev. E, 109, 054201 (2024). / arXiv:2311.17570
  5. "Lateral transport of domains in anionic lipid bilayer membranes under DC electric fields: A coarse-grained molecular dynamics study"
    Hiroaki Ito, Naofumi Shimokawa, and Yuji Higuchi
    J. Phys. Chem. B, 127, 8860-8868 (2023). / arXiv:2304.01679
  6. "Horizontal transport in the bouncing ball system with a sawtooth-shaped table"
    Yudai Okishio, Hiroaki Ito, and Hiroyuki Kitahata
    Physica D: Nonlinear Phenomena, 453, 133754:1-12 (2023). / arXiv:2201.06873
  7. "Coarse-grained molecular dynamics simulation of cation distribution profiles on negatively charged lipid membranes during phase separation"
    Yuji Higuchi, Klemen Bohinc, Jurij Reščič, Naofumi Shimokawa, and Hiroaki Ito
    Soft Matter, 19, 3640-3651 (2023).
  8. "Two-dimensional hydrodynamic simulation for synchronization in coupled density oscillators"
    Nana Takeda, Hiroaki Ito, and Hiroyuki Kitahata
    Phys. Rev. E, 107, 034201:1-11 (2023). / arXiv:2210.09762
  9. "Endocytosis-like vesicle fission mediated by a membrane-expanding molecular machine enables virus encapsulation for in vivo delivery"
    Noriyuki Uchida, Yunosuke Ryu, Yuichiro Takagi, Ken Yoshizawa, Kotono Suzuki, Yasutaka Anraku, Itsuki Ajioka, Naofumi Shimokawa, Masahiro Takagi, Norihisa Hoshino, Tomoyuki Akutagawa, Teruhiko Matsubara, Toshinori Sato, Yuji Higuchi, Hiroaki Ito, Masamune Morita, and Takahiro Muraoka
    J. Am. Chem. Soc., 145, 6210-6220 (2023).
  10. "Bifurcation structure of the flame oscillation"
    Yuki Araya, Hiroaki Ito, and Hiroyuki Kitahata
    Phys. Rev. E, 105, 044208:1-10 (2022). / arXiv:2112.07240
  11. "Anisotropic, degradable polymer assemblies driven by a rigid hydrogen-bonding motif that induce shape-specific cell responses"
    Kazuki Fukushima, Kodai Matsuzaki, Masashi Oji, Yuji Higuchi, Go Watanabe, Yuki Suzuki, Moriya Kikuchi, Nozomi Fujimura, Naofumi Shimokawa, Hiroaki Ito, Takashi Kato, Seigou Kawaguchi, and Masaru Tanaka
    Macromolecules, 55, 15-25 (2022).
  12. "Fabrication of microparticles with front-back asymmetric shapes using anisotropic gelation"
    Dongkyu Lee, Hiroyuki Kitahata, and Hiroaki Ito
    Micromachines, 12, 1121:1-11 (2021). (Open Access)
  13. "Three-phase coexistence in binary charged lipid membranes in a hypotonic solution"
    Jungyu Guo, Hiroaki Ito, Yuji Higuchi, Klemen Bohinc, Naofumi Shimokawa, and Masahiro Takagi
    Langmuir, 37, 9683-9693 (2021). / arXiv:2012.10698
    Selected as Journal Front Cover
  14. "The CR9 element is a novel mechanical load-responsive enhancer that regulates natriuretic peptide genes expression"
    Yohei Miyashita, Osamu Tsukamoto, Ken Matsuoka, Kenta Kamikubo, Yuki Kuramoto, Hai Ying Fu, Tomoya Tsubota, Hirona Hasuike, Toshio Takayama, Hiroaki ito, Tatsuro Hitsumoto, Chisato Okamoto, Hidetaka Kioka, Ryohei Oya, Haruki Shinoyama, Hideyuki Hakui, Yasunori Shintani, Hisakazu Kato, Masafumi Kitakaze, Yasufumi Sakata, Yoshihiro Asano, and Seiji Takashima
    FASEB J., 35, e21495:1-19 (2021). (Open Access)
  15. "Rotational manipulation of a microscopic object inside a microfluidic channel"
    Hiroyuki Harada, Makoto Kaneko, and Hiroaki Ito
    Biomicrofluidics, 14, 054106:1-9 (2020). (Open Access)
  16. "Spontaneous deformation and fission of oil droplets on an aqueous surfactant solution"
    Masahide Okada, Yutaka Sumino, Hiroaki Ito, and Hiroyuki Kitahata
    Phys. Rev. E, 102, 042603:1-8 (2020). / arXiv:2002.00644
  17. "Local bifurcation structure of a bouncing ball system with a piecewise polynomial function for table displacement"
    Yudai Okishio, Hiroaki Ito, and Hiroyuki Kitahata
    Chaos, 30, 083128:1-8 (2020). / arXiv:2004.10633
  18. "Bifurcation analysis of a density oscillator using two-dimensional hydrodynamic simulation"
    Nana Takeda, Naoko Kurata, Hiroaki Ito, and Hiroyuki Kitahata
    Phys. Rev. E, 101, 042216:1-7 (2020). / arXiv:1912.11806
  19. "Experimental study on the bifurcation of a density oscillator depending on density difference"
    Hiroaki Ito, Taisuke Itasaka, Nana Takeda, and Hiroyuki Kitahata
    EPL (Europhysics Letters), 129, 18001:1-7 (2020). / arXiv:1910.11573 / Full text (ResearchGate)
  20. "Coarse-grained molecular dynamics simulation for uptake of nanoparticles into a charged lipid vesicle dominated by electrostatic interactions"
    Naofumi Shimokawa, Hiroaki Ito, and Yuji Higuchi
    Phys. Rev. E, 100, 012407:1-14 (2019). / arXiv:1812.10658 / Full text (ResearchGate)
  21. "Hemoglobin S and C affect biomechanical membrane properties of P. falciparum-infected erythrocytes"
    Benjamin Fröhlich, Julia Jäger, Christine Lansche, Cecilia P. Sanchez, Marek Cyrklaff, Bernd Buchholz, Serge Theophile Soubeiga, Jacque Simpore, Hiroaki Ito, Ulrich S. Schwarz, Michael Lanzer, and Motomu Tanaka
    Commun. Biol., 2, 311:1-11 (2019).
  22. "Deformation of a red blood cell in a narrow rectangular microchannel"
    Naoki Takeishi, Hiroaki Ito, Makoto Kaneko, and Shigeo Wada
    Micromachines, 10, 199:1-15 (2019).
  23. "自動細胞品質評価のためのOn-chip対象物位置制御システムの最適化"
    伊藤弘明, 小宮拓也, 洞出光洋, 高山俊男, 金子真
    再生医療とリハビリテーション, 1, 1-8 (2018).
  24. "On-chip density mixer enhanced by air chamber"
    Toshio Takayama, Hiroki Miyashiro, Chia-Hung Dylan Tsai, Mitsuhiro Horade, Hiroaki Ito, and Makoto Kaneko
    Biomicrofluidics, 12, 044108:1-11 (2018).
  25. "LED-CT scan for pH distribution on a cross-section of cell culture medium"
    Nobuya Higashino, Toshio Takayama, Hiroaki Ito, Mitsuhiro Horade, Yasutaka Yamaguchi, Chia-Hung Dylan Tsai, and Makoto Kaneko
    Sensors, 18, 191:1-10 (2018). / Full text (ResearchGate)
  26. "Adsorption of galloyl catechin aggregates significantly modulates membrane mechanics in absence of biochemical cues"
    Takahisa Matsuzaki, Hiroaki Ito, Veronika Chevyreva, Ali Makky, Stefan Kaufmann, Kazuki Okano, Naritaka Kobayashi, Masami Suganuma, Seiichiro Nakabayashi, Hiroshi Y. Yoshikawa, and Motomu Tanaka
    Phys. Chem. Chem. Phys., 19, 19937-19947 (2017). / Full text (ResearchGate)
  27. "Red blood cell responses during a long-standing load in a microfluidic constriction"
    Mitsuhiro Horade, Chia-Hung Dylan Tsai, Hiroaki Ito, and Makoto Kaneko
    Micromachines, 8, 100:1-10 (2017). / Full text (ResearchGate)
  28. "Mechanical diagnosis of human erythrocytes by ultra-high speed manipulation unraveled critical time window for global cytoskeletal remodeling"
    Hiroaki Ito, Ryo Murakami, Shinya Sakuma, Chia-Hung Dylan Tsai, Thomas Gutsmann, Klaus Brandenburg, Johannes M. B. Pöschl, Fumihito Arai, Makoto Kaneko, and Motomu Tanaka
    Sci. Rep., 7, 43134:1-14 (2017). / Full text (ResearchGate)
    Press Release: Osaka University / Kyoto University / NIKKEI / NIKKEISANGYOU (28.02.2017)/ mynavi NEWS / EurekAlert! (in English) / MedicalXpress (in English) / AlphaGalileo (in English)
  29. "Coarse-grained molecular dynamics simulation of binary charged lipid membranes: Phase separation and morphological dynamics"
    Hiroaki Ito, Yuji Higuchi, and Naofumi Shimokawa
    Phys. Rev. E, 94, 042611:1-11 (2016). / arXiv:1607.06167 / Full text (ResearchGate)
  30. "An on-chip RBC deformability checker significantly improves velocity-deformation correlation"
    Chia-Hung Dylan Tsai, Junichi Tanaka, Makoto Kaneko, Mitsuhiro Horade, Hiroaki Ito, Tatsunori Taniguchi, Tomohito Ohtani, and Yasushi Sakata
    Micromachines, 7, 176:1-13 (2016). / Full text (ResearchGate)
    Press Release: Osaka University / Yomiuri Online / JIJI.COM
  31. "Tracking mechanical and morphological dynamics of regenerating hydra tissue fragments using a two fingered micro-robotic hand"
    Mariam Veschgini,† Florian Gebert,† Nyamdorj Khangai,† Hiroaki Ito, Ryo Suzuki, Thomas W. Holstein, Yasushi Mae, Tasuo Arai, and Motomu Tanaka (†equally contributed)
    Appl. Phys. Lett., 108, 103702:1-4 (2016). / Full text (ResearchGate)
  32. "Non-periodic oscillatory deformation of an actomyosin microdroplet encapsulated within a lipid interface"
    Yukinori Nishigami,† Hiroaki Ito,† Seiji Sonobe, and Masatoshi Ichikawa (†equally contributed)
    Sci. Rep., 6, 18964:1-11 (2016). / Full text (ResearchGate)
  33. "Coupling between pore formation and phase separation in charged lipid membranes"
    Hiroki Himeno, Hiroaki Ito, Yuji Higuchi, Tsutomu Hamada, Naofumi Shimokawa, and Masahiro Takagi
    Phys. Rev. E, 92, 062713:1-12 (2015). / arXiv:1504.06039 / Full text (ResearchGate)
  34. "Wrinkling of a spherical lipid interface induced by actomyosin cortex"
    Hiroaki Ito,† Yukinori Nishigami,† Seiji Sonobe, and Masatoshi Ichikawa (†equally contributed)
    Phys. Rev. E, 92, 062711:1-8 (2015). / arXiv:1505.04371 / Full text (ResearchGate)
  35. "Droplet-Shooting and Size-Filtration (DSSF) Method for Synthesis of Cell-Sized Liposomes with Controlled Lipid Compositions"
    Masamune Morita, Hiroaki Onoe, Miho Yanagisawa, Hiroaki Ito, Masatoshi Ichikawa, Kei Fujiwara, Hirohide Saito, and Masahiro Takinoue
    ChemBioChem, 16, 2029-2035 (2015).
  36. "Quantification of the influence of endotoxins on the mechanics of adult and neonatal red blood cells"
    Hiroaki Ito, Navina Kuss, Bastian E. Rapp, Masatoshi Ichikawa, Thomas Gutsmann, Klaus Brandenburg, Johannes M. B. Pöschl, and Motomu Tanaka
    J. Phys. Chem. B, 119, 7837-7845 (2015). / Full text (ResearchGate)
  37. "Dynamical formation of lipid bilayer vesicles from lipid-coated droplets across a planar monolayer at an oil/water interface"
    Hiroaki Ito, Toru Yamanaka, Shou Kato, Tsutomu Hamada, Masahiro Takagi, Masatoshi Ichikawa, and Kenichi Yoshikawa
    Soft Matter, 9, 9539-9547 (2013). / Full text (ResearchGate)
    Selected as Journal Front Cover
    Highlighted as September's Hot Papers in RSC publishing blog and 2013 Hot Papers
  38. "Emergence of a thread-like pattern with charged phospholipids on an oil/water interface"
    Hiroaki Ito, Miho Yanagisawa, Masatoshi Ichikawa, and Kenichi Yoshikawa
    J. Chem. Phys., 136, 204903:1-6 (2012). / Full text (ResearchGate)
    Selected as JCP Editor’s Choice for 2012

Proceedings

  1. "Experimental study on microfluidic mixing with trapezoidal obstacles in a 1000-fold span of Reynolds number"
    Xin-Yu Lin, Hiroaki Ito, Makoto Kaneko, and Chia-Hung Dylan Tsai
    2019 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS2019, Macau, China), Poster, 2441-2446 (2019).
    DOI: 10.1109/IROS40897.2019.8967691
  2. "On-chip deformability measurement of eukaryotic cells: Comparison to anucleate cells"
    Hiroaki Ito, Kohei Fujimoto, and Makoto Kaneko
    The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2019, Basel, Switzerland), Poster, 530-531 (2019).
  3. "How to measure cellular shear modulus inside a chip: Detailed correspondence to the fluid-structure coupling analysis"
    Hiroaki Ito, Naoki Takeishi, Atsushi Kirimoto, Misato Chimura, Tomohito Ohtani, Yasushi Sakata, Mitsuhiro Horade, Toshio Takayama, and Makoto Kaneko
    The 32nd International Conference on IEEE Micro Electro Mechanical System (MEMS 2019, Seoul, Korea), Poster, 433-436 (2019).
    DOI: 10.1109/MEMSYS.2019.8870772
  4. "On-chip dynamic mechanical measurement"
    Atsushi Kirimoto, Hiroaki Ito, Mitsuhiro Horade, Toshio Takayama, Misato Chimura, Tomohito Ohtani, Yasushi Sakata, and Makoto Kaneko
    The 32nd International Conference on IEEE Micro Electro Mechanical System (MEMS 2019, Seoul, Korea), Poster, 418-421 (2019).
    DOI: 10.1109/MEMSYS.2019.8870789
  5. "Deep learning assisted analysis of multiple individual red blood cells in blood flow"
    Takayuki Akai, Hiroaki Ito, and Makoto Kaneko
    The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2018, Kaohsiung, Taiwan), Oral, 197-198 (2018).
  6. "Automatically optimized on-chip feedback manipulation toward clinical use"
    Hiroaki Ito, Takuya Komiya, Mitsuhiro Horade, Toshio Takayama, and Makoto Kaneko
    The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2018, Kaohsiung, Taiwan), Poster, 1203-1204 (2018).
  7. "Development of micromanipulator with semiconductor strain gauge that can be used in solution for characteristics measurement"
    Mitsuhiro Horade, Osamu Tabata, Hiroaki Ito, Toshio Takayama, Dylan Tsai, and Makoto Kaneko
    The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2018, Kaohsiung, Taiwan), Poster, 1007-1008 (2018).
  8. "Integration of fluctuation spectroscopy into a microfluidic platform for novel cellular viscoelastic measurement"
    Hiroaki Ito, Chia-Hung Dylan Tsai, and Makoto Kaneko
    The 31st IEEE International Conference on Micro Electro Mechanical Systems (MEMS2018, Belfast, UK), Oral (acceptance rate 10.0%), 137-140 (2018).
    DOI: 10.1109/MEMSYS.2018.8346502
  9. "Measurement of both viscous and elastic constants of a red blood cell in a microchannel"
    Atsushi Kirimoto, Hiroaki Ito, Chia-Hung Dylan Tsai, and Makoto Kaneko
    The 31st IEEE International Conference on Micro Electro Mechanical Systems (MEMS2018, Belfast, UK), Poster, 388-391 (2018).
    DOI: 10.1109/MEMSYS.2018.8346569
  10. "Pressure dependency of virtual vortex gear"
    Toshio Takayama, Chia-Hung Dylan Tsai, Hiroaki Ito, and Makoto Kaneko
    The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2017, Savannah, USA), 293-294 (2017).
  11. "Red blood cell deformability in patients with heart failure"
    Misato Chimura, Tomohito Ohtani, Tatsunori Taniguchi, Takuto Ishida, Junnichi Tanaka, Hiroaki Ito, Yasumasa Tsukamoto, Makoto Kaneko, and Yasushi Sakata
    J. Card. Fail. (in The 21st Annual Scientific Meeting of the Japanese Heart Failure Society) (Akita, Japan), Oral, S31 (2017).
    DOI: https://doi.org/10.1016/j.cardfail.2017.08.134
  12. "On-Chip RBC deformability checker embedded with vision analyzer"
    Makoto Kaneko, Takuto Ishida, Chia-Hung Dylan Tsai, Hiroaki Ito, Misato Chimura, Tatsunori Taniguchi, Tomohito Ohtani, and Yasushi Sakata
    IEEE International Conference on Mechatronics and Automation (ICMA2017, Takamatsu, Japan), Oral, 2005-2010 (2017).
    DOI: 10.1109/ICMA.2017.8016126
  13. "Virtual vortex gear"
    Chia-Hung Dylan Tsai, Takayuki Akai, Mitsuhiro Horade, Hiroaki Ito, and Makoto Kaneko
    The 19th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers2017, Kaohsiung, Taiwan), Oral (acceptance rate 21.7%), Oral, 583-586 (2017).
    DOI: 10.1109/TRANSDUCERS.2017.7994116
  14. "Red blood cell deformability upon continuous or repetitive loadings"
    Hiroaki Ito, Ryo Murakami, Chia-Hung Dylan Tsai, Mitsuhiro Horade, Motomu Tanaka, and Makoto Kaneko
    The 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS2017, Las Vegas, USA), Oral (acceptance rate 9.8%), 141-144 (2017).
    DOI: 10.1109/MEMSYS.2017.7863360
  15. "Observation of cell pinball through high speed switching between reflection interference and phase contrast"
    Ryo Murakami, A. Yamamoto, Hiroaki Ito, Chia-Hung Dylan Tsai, Mitsuhiro Horade, Motomu Tanaka, and Makoto Kaneko
    The 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS2017, Las Vegas, USA), Poster, 1337-1338 (2017).
    DOI: 10.1109/MEMSYS.2017.7863667
  16. "On-chip cell gym"
    Mitsuhiro Horade, Makoto Kaneko, Chia-Hung Dylan Tsai, Hiroaki Ito, Nobuya Higashino, Takayuki Akai, Utako Yokoyama, Yoshihiro Ishikawa, Shinya Sakuma, and Fumihito Arai
    The 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS2017, Las Vegas, USA), Poster, 603-604 (2017).
    DOI: 10.1109/MEMSYS.2017.7863479
  17. ""Chameleon Effect" of RBC Under Loading in Microfluidic Channel"
    Mitsuhiro Horade, Chia-Hung Dylan Tsai, Hiroaki Ito, Motomu Tanaka, and Makoto Kaneko
    The 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2016, Dublin, Ireland), Poster, 311-312 (2016).
  18. "High-Resolution Cell Manipulation for Longstanding Load on Red Blood Cells"
    Chia-Hung Dylan Tsai, Mitsuhiro Horade, Hiroaki Ito, Motomu Tanaka, and Makoto Kaneko
    IEEE International Conference on Mechatronics and Automation (ICMA2016, Harbin, China), Poster, 914-919 (2016).
    DOI: 10.1109/ICMA.2016.7558684
  19. "Catch, Load and Launch toward On-Chip Active Cell Evaluation"
    Ryo Murakami, Chia-Hung Dylan Tsai, Hiroaki Ito, Motomu Tanaka, Shinya Sakuma, Fumihito Arai, and Makoto Kaneko
    2016 IEEE International Conference on Robotics and Automation (ICRA2016, Stockholm, Sweden), Poster, TuDaT3.4, 1713-1718 (2016).
    DOI: 10.1109/ICRA.2016.7487314

Books

  1. "Fabrication of implantable human arterial graft by periodic hydrostatic pressure"
    Junichi Saito, Utako Yokoyama, Toshio Takayama, Hiroaki Ito, Tomomi Tadokoro, Yoshinobu Sugo, Kentaro Kurasawa, Miyuki Ogawa, Etsuko Miyagi, Hideki Taniguchi, Makoto Kaneko, and Yoshihiro Ishikawa Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension (Springer Open), Chap.46 (2020).

Reviews

  1. "Chemically artificial rovers based on self-propelled droplets in micrometer-scale environment"
    Taro Toyota, Hironori Sugiyama, Soichiro Hiroi, Hiroaki Ito, and Hiroyuki Kitahata
    Curr. Opin. Colloid Int. Sci., 49, 60-69 (2020).
  2. "On-chip cell manipulation and applications to deformability measurements"
    Hiroaki Ito and Makoto Kaneko
    ROBOMECH J., 7, 3:1-11 (2020).
  3. "Active materials integrated with actomyosin"
    Hiroaki Ito, Masahiro Makuta, Yukinori Nishigami, and Masatoshi Ichikawa
    J. Phys. Soc. Jpn., 86, 101001:1-6 (2017).

Overview articles

  1. "Editorial for the special issue on advances in microfluidics for quantifying cell mechanics and biotransport"
    Hiroaki Ito and Naoki Takeishi
    Micromachines, 13, 1127 (2022).
  2. "荷電脂質膜の秩序形成：実験と粗視化分子動力学シミュレーションの融合"
    下川直史、伊藤弘明、樋口祐次
    アンサンブル, 23, (No.4, 10月号) 253-259 (2021). (in Japanese)
  3. "深層学習を利用した赤血球細胞集団の流れ解析"
    Hiroaki Ito
    C & I Commun., 45(2), 5-6 (2020). (in Japanese)
  4. "荷電脂質膜ベシクルの相分離・自発的変形・ナノ粒子の透過"
    下川直史、伊藤弘明、樋口祐次
    C & I Commun., 44(4), 17-20 (2019). (in Japanese)
  5. "非平衡界面現象の観点からみる生細胞の力学応答"
    Hiroaki Ito
    C & I Commun., 44(3), 40-42 (2019). (in Japanese)
  6. "Mechanism of bleb-driven amoeboid locomotion"
    Yukinori Nishigami, Hiroaki Ito, and Masatoshi Ichikawa
    Jpn. J. Protozool, 49, (2016). (in Japanese)
  7. "Studies on bleb-driven cell locomotion using reconstituted systems"
    Yukinori Nishigami, Hiroaki Ito, and Masatoshi Ichikawa
    植物科学の最前線 (BSJ-Review), 6, 82-91 (2015). (in Japanese)
  8. "油水界面上の中性・荷電脂質混合膜のパターン・ダイナミクス"
    Hiroaki Ito
    日本数理生物学会ニュースレター, 64, 3 (2011). (in Japanese)

Presentations

Talks (invited)

  1. "変形粒子懸濁液の擬2次元流れにおける流動性と変形配向秩序"
    伊藤弘明
    日本流体力学会年会2024、2024年9月25日 (in Japanese)
  2. "人工細胞膜における荷電脂質分子の相分離とドメイン輸送"
    伊藤弘明、下川直史、樋口祐次
    細胞を創る研究会16.0、2023年9月25日 (in Japanese)
  3. "Orientational order of deformable microparticles under a quasi-two-dimensional flow"
    Hiroaki Ito
    Japan-China Workshop on Bio-Soft Matter 2023 (Chiba University), Sep 1, 2023
  4. "On-chip manipulation platform for deformability measurements of red blood cells"
    Hiroaki Ito
    8th Ajou-Chiba Joint Symposium (Chiba University), Feb 10, 2023
  5. "Fabrication of microparticles with front-back asymmetric shapes by droplet-based microfluidics"
    Hiroaki Ito, Dongkyu Lee, and Hiroyuki Kitahata
    International Conference on Advanced Mechanism and Machine Technology 2021 (iCMMT2021, Hsinchu), Oct 30, 2021
  6. "On-chip manipulation for revealing novel aspects of red blood cell mechanics"
    Hiroaki Ito
    The 2nd Joint Meeting of The European Society for Clinical Hemorheology and Microcirculation, The International Society for Clinical Hemorheology, and The International Society of Biorheology (ESCHM-ISCH-ISB 2021 FUKUOKA), July 7, 2021
  7. "マイクロ流体デバイスを用いた血球細胞の物性評価"
    伊藤弘明
    分子キラリティー研究センター定例会、2021年5月20日 (in Japanese)
  8. "オンチップ高精度操作が引き出す赤血球の時空間力学特性"
    伊藤弘明
    時空間秩序・生命物理科学研究会（同志社びわこトリートセンター）、Mar 4, 2017 (in Japanese)
  9. "オンチップ高精度操作が引き出す赤血球の新奇力学物性"
    伊藤弘明
    非線形ソフトマター研究会2016（横浜市民ふれあいの里）、Oct 29, 2016 (in Japanese)
  10. "Approach to self-propelled artificial cells from microdroplets"
    Hiroaki Ito
    Symposium on The 53rd Annual Meeting of the Biophysical Society of Japan, Sept 15, 2015

Conference talks/Posters

Frequent

Others

Outreach

  1. "人工毛細血管を流れる赤血球を見る・操作する・測る" (in Japanese)
    Hiroaki Ito
    Public lecture: ひらめき☆ときめきサイエンス"髪の毛の1/20の太さ!ナノテクノロジーで人工毛細血管をつくってみよう!", Jul 30, 2021
  2. "《千葉大学研究紹介》理学部物理学科" (in Japanese)
    Chiba University YouTube Official Channel, Nov 25, 2020
  3. "赤血球の神秘的挙動を見てみよう" (in Japanese)
    Hiroaki Ito
    Public lecture: 細胞エクササイズが拓く新世界, Nov 10, 2016

Grants

04.2024 - 03.2027 Grant-in-Aid for Scientific Research (C) (JSPS)
04.2021 - 03.2023 JSPS Bilateral Joint Research Projects (MESS, Slovenia)
04.2021 - 03.2024 Grants-in-Aid for the Japan Society for the Promotion of Science (JSPS) Early-Career Scientists
04.2019 - 03.2021 Grants-in-Aid for the Japan Society for the Promotion of Science (JSPS) Early-Career Scientists
11.2018 - 11.2019 Grant for Basic Science Research Projects
04.2018 - 03.2021 Grants-in-Aid for the Japan Society for the Promotion of Science (JSPS) Research Fellowship for Young Scientists (PD)
01.2018 MEMS2018 Young Researcher Travel Grant
07.2017 - 03.2019 JSPS KAKENHI Challenging Research (Pioneering)
08.2016 - 03.2018 Grant-in-Aid for Research Activity Start-up (JSPS) (completed by 07.2017)
04.2016 - 03.2017 Sasakawa Scientific Research Grant, The Japan Science Society
04.2013 - 03.2016 Grants-in-Aid for the Japan Society for the Promotion of Science (JSPS) Research Fellowship for Young Scientists (DC1)
2011.07 - 2012.03 Kyoto University Venture Business Laboratory (grants-in-aid program for young reserachers)

Awards

SI2018 Oral Presentation Award (Measurement of a red blood cell viscoelasticity for micro-deformation in short period)
SI2018 Oral Presentation Award (Influence of red blood cell mechanics on two-dimensional blood flow)
Oral Presentation Award for Young Researchers, The 69th Divisional Meeting of Division of Colloid and Surface Chemistry
Robotics and Mechatronics Division, Certificate of Merit for ROBOMECH Outstanding Research Activity, The Robotics and Mechatronics Conference 2017 (ROBOMECH2017)
Best Poster Award, 4th Kyoto Young Researchers Workshop on Softmatter
JCP Editor’s Choice for 2012

Affiliated academic organizations

The Physical Society of Japan
The Biophysical Society of Japan
The Chemical Society of Japan, Division of Colloid and Surface Chemistry
The Japan Society of Mechanical Engineers

Biography

03.2007 - 03.2011 Faculty of Science, Kyoto University
04.2011 - 03.2013 Department of Physics, Graduate School of Science, Kyoto University (MC)
    08.2012 - 10.2012     Curie Institute, France
04.2013 - 03.2016 Department of Physics, Graduate School of Science, Kyoto University (DC), Ph.D (Science)
JSPS Research Fellowship for Young Scientists (DC1)
    12.2013 - 02.2014     University of Heidelberg, Germany（Externally supervised）
    09.2014 - 10.2014     University of Heidelberg, Germany
04.2016 - 03.2018 Department of Mechanical Engineering, Graduate School of Engineering, Osaka University, Postdoctral Fellow
04.2018 - 02.2019 JSPS Research Fellow (PD) / Visiting Researher at Osaka University
03.2019 - present Department of Physics, Graduate School of Science, Chiba University, Assistant Professor

Contact

e-mail:
address: 263-8522
Yayoi-cho 1-33, Inage-ku, Chiba, Japan
401 in 2nd Bld., Faculty of Science, Chiba University
researchmap: >> Hiroaki Ito
ResearchGate: >> Hiroaki Ito